12) PhD student – from 2021 – Supervision rate: 100%

Mariska BANIDOL

Thesis title : Evaluating DESI for chemical imaging of digital fingerprints in forensic investigations, defense scheduled in 2026

Research performed in parallel to her commitment as a police officer (Capitaine de Gendarmerie au Pôle Judiciaire de la Gendarmerie Nationale)

Associated scientific production:

1. Mariska Banidol, Sophia Kouider, Isaure Sergent, Hélène Pizzala, Laurence Charles. Desorption electrospray ionization mass spectrometry imaging of latent fingerprints revealed by Oil Red O. Rapid Commun. Mass Spectrom. 2024, 38 (8) e9724. DOI: 10.1002/rcm.9724

11) PhD Student – 2021-2024 – Supervision rate: 70% (with Dr Anouk Gaudel-Siri, AMU)

Isaure SERGENT

Thesis title : Coupling ion mobility spectrometry with tandem mass spectrometry to increase the reading throughput of digital polymers, defended on September 26, 2024

Associated scientific production:

7. Isaure Sergent, Thibault Schutz, Jean-François Lutz, Laurence Charles. Using ion mobility spectrometry to understand signal dilution during MS/MS sequencing of digital polymers: experimental evidence of intramolecular cyclization. Rapid Commun. Mass Spectrom. 2024, 38 (17) e9852. DOI: 10.1002/rcm.9852

6. Isaure Sergent, Thibault Schutz, Laurence Oswald, Georgette Obeid, Jean-François Lutz, Laurence Charles. Using nitroxides to model the ion mobility behavior of nitroxide-ended oligomers: a bottom-up approach for prediction of IMS separation. J. Am. Soc. Mass Spectrom. 2024, 35 (3) 534-541. DOI: 10.1021/jasms.3c00393

5. Thibault Schutz, Isaure Sergent, Georgette Obeid, Laurence Oswald, Abdelaziz Al Ouahabi, Paul N. W. Baxter, Jean-Louis Clément, Didier Gigmes, Laurence Charles, Jean-François Lutz. Conception and evaluation of a library of cleavable mass tags for digital polymers sequencing. Angew. Chem. Int. Ed. 2023, 62 (45) e202310801. DOI: 10.1002/anie.202310801

4. Itab Youssef, Svetlana Samokhvalova, Isaure Sergent, Laurence Charles, Jean-François Lutz. Informational polymers with precise carbamate sequences. Precision Chem. 2023, 1 (8) 480-484. DOI: 10.1021/prechem.3c00077

3. Isaure Sergent, Abel Adjieufack, Anouk Gaudel-Siri, Didier Siri, Laurence Charles. The IMSCal approach to determine collision cross section of multiply charged anions in traveling wave ion mobility spectrometry. Int. J. Mass Spectrom. 2023, 492, 117112. DOI: 10.1016/j.ijms.117112

2. Itab Youssef, Isaure Carvin-Sergent, Evgeniia Konishcheva, Seydina Kebe, Vincent Greff, Denise Karamessini, Maziar Matloubi, Abdelaziz Al Ouahabi, Jochen Moesslein, Jean-Arthur Amalian, Salomé Poyer, Laurence Charles, Jean-François Lutz. Covalent attachment and detachment by reactive-DESI of sequence-coded polymer taggants. Macromol. Rapid Commun. 2022, 43 (21) 202200412. DOI: 10.1002/marc.202200412

1. Ian Roszak, Laurence Oswald, Abdelaziz Al Ouahabi, Annabelle Bertin, Eline Laurent, Olivier Felix, Isaure Carvin-Sergent, Laurence Charles, Jean-François Lutz. Synthesis and sequencing of informational poly(aminophosphodiester)s. Polym. Chem. 2021, 12 (37) 5279-5282. DOI: 10.1039/d1py01052b

Awards:
“Journal of Mass Spectrometry” award at IMSC 2024 in Melbourne, Australia
“best 2023 oral” award from the Young Scientists from the French Society for Mass Spectrometry
“2023 student poster” award from Waters at SCM-10 in Amsterdam, NL

Current position: Application for post-doctoral positions

10) PhD Student – 2016-2019 – Supervision rate: 100%

Jean-Arthur AMALIAN

Thesis title : MS/MS sequencing methodologies to read encoded polymers, defended on September 5, 2019

Associated scientific production:

9. Eline Laurent, Jean-Arthur Amalian, Marie Parmentier, Laurence Oswald, Abdelaziz Al Ouahabi, Florent Dufour, Kevin Launay, Jean-Louis Clément, Didier Gigmes, Marc-André Delsuc, Laurence Charles, Jean-François Lutz. High-capacity digital polymers: storing images in single molecules. Macromolecules 2020, 53 (10) 4022-4029. DOI:10.1021/acs.macromol.0c00666

8. Jean-Arthur Amalian, Gianni Cavallo, Abdelaziz Al Ouahabi, Jean-François Lutz, Laurence Charles. Revealing data encrypted in sequence-controlled poly(alkoxyamine phosphodiester)s by combining ion mobility with tandem mass spectrometry. Anal. Chem. 2019, 91 (11) 7266-7272. DOI: 10.1021/acs.analchem.9b00813

7. Laurence Oswald, Abdelaziz Al Ouahabi, Chloé Laure, Jean-Arthur Amalian, Laurence Charles, Jean-François Lutz. Universal soluble polymer supports with precisely controlledloading capacity for sequence-defined oligomer synthesis. J. Polym. Sci. A, Polym. Chem.2019, 57 (3) 403-410. DOI: 10.1002/pola.29218

6. Gianni Cavallo, Salomé Poyer, Jean-Arthur Amalian, Florent Dufour, Alexandre Burel, Christine Carapito, Laurence Charles, Jean-François Lutz. Cleavable binary-dyads: simplifyingdata-extraction and increasing data storage density in digital polymers. Angew. Chem. Int. Ed.2018, 57 (21) 6266-6269. DOI: 10.1002/anie.201803027

5. Jean-Arthur Amalian, Abdelaziz Al Ouahabi, Gianni Cavallo, Niklas F. König, Salomé Poyer, Jean-François Lutz, Laurence Charles. Controlling the structure of sequence-defined poly(phosphodiester)s for optimal MS/MS reading of digital information. J. Mass Spectrom. 2017, 52 (11) 788-798. DOI: 10.1002/jms.3947

4. Jean-Arthur Amalian, Salomé Poyer, Benoit E. Petit, Sofia Telitel, Valérie Monnier, Denise Karamessini, Didier Gigmes, Jean-François Lutz, Laurence Charles. Negative mode MS/MS to read digital information encoded in sequence-defined oligo(urethane)s: a mechanistic study. Int. J. Mass Spectrom. 2017, 421, 271-278. DOI: 10.1016/j.ijms.2017.07.006

3. Abdelaziz Al Ouahabi, Jean-Arthur Amalian, Laurence Charles, Jean-François Lutz. Mass spectrometry sequencing of long digital polymers facilitated by programmed inter-byte fragmentation. Nat. Commun. 2017, 8, 967. DOI: 10.1038/s41467-017-01104-3

2. IUfuk S. Gunay, Benoit E. Petit, Denise Karamessini, Abdelaziz Al Ouahabi, Jean-Arthur Amalian, Christophe Chendo, Michel Bouquey, Didier Gigmes, Laurence Charles, Jean-François Lutz. Chemoselective synthesis of uniform sequence-coded polyurethanes and their use as molecular tags. Chem 2016, 1, 114-126. DOI: 10.1016/j.chempr.2016.06.006

1. Jean-Arthur Amalian, Thanh T. Trinh, Jean-François Lutz, Laurence Charles. MS/MS digital readout: analysis of binary information encoded in the monomer sequences of poly(triazoleamide)s. Anal. Chem. 2016, 88 (7) 3715-3722. DOI: 10.1021/acs.analchem.5b04537

Awards:
“2020 best thesis” award from the French Society for Mass Spectrometry
“2020 best thesis in analytical chemistry” award from the French Chemical Society

Current position: Scientific manager, R&D Department, Sanofi, Aramon, France

9) PhD Student – 2013-2016 – Supervision rate: 66% (with Dr Aura Tintaru, AMU)

Christophe CHENDO

Thesis title : MS/MS sequencing methodolMultidimensional approach in MALDI mass spectrometry for structuralcharacterization of synthetic polymersogies to read encoded polymers, defended on December 15, 2016

Associated scientific production:

5. Christophe Chendo, Laurence Charles. Generation of doubly charged species from small synthetic polymers in a high pressure MALDI source. Int. J. Mass Spectrom. 2017, 416, 46-52. DOI: 10.1016/j.ijms.2016.11.010

4. Christophe Chendo, Le Dao, Trang N. T. Phan, Didier Gigmes, Laurence Charles.Multidimensional mass spectrometry to characterize degradation products generated duringMALDI of polystyrenes prepared by controlled radical polymerization techniques. J. Polym.Sci. A, Polym. Chem. 2016, 54 (20) 3388-3397. DOI: 10.1002/pola.28229

3. Christophe Chendo, Trang N. T. Phan, Sylvain R. A. Marque, Didier Gigmes, Laurence Charles. Mass spectrometry of nitroxide-mediated poly(4-vinylpyridine): a case of unwanted reactive MALDI. Int. J. Mass Spectrom. 2016, 405, 50-58. DOI: 10.1016/j.ijms.2016.05.015

2. Christophe Chendo, Guillaume Moreira, Aura Tintaru, Paola Posocco, Erik Lausini, Catherine Lefay, Didier Gigmes, Stéphane Viel, Sabrina Pricl, Laurence Charles. Anomerization of acrylated glucose during travelling wave ion mobility spectrometry. J. Am. Soc. Mass Spectrom. 2015, 26 (9) 1483-1493. DOI: 10.1007/s13361-015-1170-6

1. Christophe Chendo, Marion Rollet, Trang N. T. Phan, Stéphane Viel, Didier Gigmes,Laurence Charles. Successful MALDI mass spectrometry of poly(4-vinylpyridine) using asolvent-free sample preparation. Int. J. Mass Spectrom. 2015, 376, 90-96. DOI:10.1016/j.ijms.2014.12.004

Current position: CNRS technical staff at ESPCI, Paris, France

8) PhD Student – 2012-2015 – Supervision rate: 50% (with Dr L Peng, AMU)

Chao CHEN

Thesis title : Amphiphilic dendrimers for siRNA delivery, defended on September 29, 2015

Associated scientific production:

2. Xiaoxuan Liu, Yang Wang, Chao Chen, Aura Tintaru, Yu Cao, Juan Liu, Fabio Ziarelli, JingjieTang, Hongbo Guo, Roselyne Rosas, Suzanne Giorgio, Laurence Charles, Palma Rocchi, LingPeng. A fluorinated bola-amphiphilic dendrimer for on-demand delivery of siRNA via specificresponse to reactive oxygen species. Adv. Funct. Mater. 2016, 26 (47) 8594-8603.DOI:10.1002/adfm.201604192

1. Aura Tintaru, Rémi Ungaro, Xiaoxiuan Liu, Chao Chen, Laurent Giordano, Ling Peng,Laurence Charles. Structural characterization of new defective molecules in poly(amidoamine)dendrimers: a formaldehyde-induced modification during divergent synthesis in methanol.Anal. Chim. Acta 2015, 853 (1) 451-459. DOI: 10.1016/j.aca.2014.10.048

Current position: Senior scientist, Shanghai Bioduro Biologics Co, Shanghai, P.R. China

7) PhD Student – 2009-2012 – Supervision rate: 50% (with Dr F. Aubriet, Univ. Metz)

Thierry FOUQUET

Thesis title : Mass spectrometry of synthetic polysiloxanes. From linear models to plasma-polymer network, defended on December 14, 2012

Associated scientific production:

9. Thierry Fouquet, David Ruch, Laurence Charles. Collision-induced cage folding of partially condensed polyhedral oligomeric silsesquioxanes (POSS) bearing naked and capped silanols. Rapid Commun. Mass Spectrom. 2014, 28 (16) 1849-1852. DOI: 10.1002/rcm.6967

8. Thierry Fouquet, Valérie Tonazzio, David Ruch, Laurence Charles. Use of doubly chargedprecursors to study dissociation mechanisms of singly charged poly(dimethylsiloxane)oligomers with different end-groups. J. Am. Soc. Mass Spectrom. 2013, 24 (7) 1123-1129.DOI: 10.1007/s13361-013-0665-2

7. Thierry Fouquet, Julien Petersen, Fabio Ziarelli, Jérôme Bour, Valérie Tonazzio, David Ruch, Laurence Charles. Insights in the architecture of silicon-based plasma-polymers using partial network ethanolysis combined to electrospray tandem mass spectrometry. Plasma Process. Polym. 2013, 10 (3) 271-284. DOI: 10.1002/ppap.201200129

6. Thierry Fouquet, Christophe Chendo, Valérie Toniazzo, David Ruch, Laurence Charles. Collision-induced dissociation of synthetic polymers containing hydride groups: the case of poly(hydromethylsiloxane) homopolymers and poly(hydromethylsiloxane)-co-(dimethylsiloxane) co-polymers. Rapid Commun. Mass Spectrom. 2013, 27 (1) 88-96. DOI:10.1002/rcm.6432

5. Thierry Fouquet, Jérôme Bour, Valérie Tonazzio, David Ruch, Laurence Charles. Characterization of ethanolysis of products of poly(dimethylsiloxane) species by electrospray ionization tandem mass spectrometry. Rapid Commun. Mass Spectrom. 2012, 26 (17) 2057-2067. DOI: 10.1002/rcm.6317

4. Thierry Fouquet, Trang N. T. Phan, Laurence Charles. Tandem mass spectrometry ofelectrosprayed polyhedral oligomeric silsesquioxane compounds with different substituents.Rapid Commun. Mass Spectrom. 2012, 26 (7) 765-774. DOI:10.1002/rcm.6159

3. Thierry Fouquet, Julien Petersen, Joao A. S. Bomfim, Fabio Ziarelli, David Ruch, Laurence Charles. Electrospray tandem mass spectrometry combined with authentic compound synthesis for structural characterization of an octamethylcyclotetrasiloxane plasma polymer. Int. J. Mass Spectrom. 2012, 313, 58-67. DOI: 10.1016/j.ijms.2012.01.007

2. Thierry Fouquet, Stéphane Humbel, Laurence Charles. Dissociation characteristics of α,ω-dihydride poly(dimethylsiloxane) ammonium adducts generated by electrospray ionization. Int. J. Mass Spectrom. 2011, 306 (1) 70-76. DOI: 10.1016/j.ijms.2011.06.020

1. Thierry Fouquet, Stéphane Humbel, Laurence Charles. Tandem mass spectrometry oftrimethylsilyl-terminated poly(dimethylsiloxane) ammonium adducts generated by electrosprayionization. J. Am. Soc. Mass Spectrom. 2011, 22 (4) 649-658. DOI: 10.1007/s13361-010-0073-9

Awards:
“2012 best thesis in chemistry” award from Aix Marseille Université
“2012 best thesis” award from the French Society for Mass Spectrometry
“2012 best student paper award” from International Journal of Mass Spectrometry

Current position: Scientific manager, R&D Department, Bausch & Lomb, Rochester, NY, USA

6) PhD Student – 2008-2011 – Supervision rate: 50% (with Dr S Viel)

Caroline BARRERE

Thesis title : Methodological developments in mass spectrometry and nuclear magneticresonance for structural characterization of block copolymers, defended on August 26, 2011

Associated scientific production:

3. Caroline Barrère, Christophe Chendo, Trang N. T. Phan, Valérie Monnier, Thomas Trimaille, Stéphane Humbel, Stéphane Viel, Didier Gigmes, Laurence Charles. Successful MALDI-MS analysis of synthetic polymers with labile end-groups – The case of nitroxide mediated polymerization using the MAMA-SG1 alkoxyamine. Chem. Eur. J. 2012, 18 (25) 7916-7924. DOI: 10.1002/chem.201200239

2. Caroline Barrère, Michaël Mazarin, Rémi Giordanengo, Trang N. T. Phan, André Thévand, Stéphane Viel, Laurence Charles. Molecular weight determination of Block Copolymers byPulsed Gradient Spin-Echo NMR. Anal. Chem. 2009, 81 (19) 8054-8060. DOI:10.1021/ac9018654

1. Hélène Pizzala, Caroline Barrère, Michaël Mazarin, Fabio Ziarelli, Laurence Charles. Solid-state NMR as a tool to explore MALDI sample. J. Am. Soc. Mass Spectrom. 2009, 20 (10)1906-1911. DOI: 10.1016/j.jasms.2009.06.021

Awards:
“2011 best thesis in chemistry” award from Aix Marseille Université
“2011 best thesis in analytical chemistry” award from the French Chemical Society

Current position: Scientific manager, R&D Department, Bausch & Lomb, Rochester, NY, USA

5) PhD Student – 2007-2010 – Supervision rate: 50% (with Dr B Tuccio)

Mathilde TRIQUIGNEAUX

Thesis title : Combining electron paramagnetic resonance with mass spectrometry toidentify nitroxydes and associated diamagnetic species – Application to mechanistic studies, defended on September 3, 2010

Associated scientific production:

6. Mathilde Triquigneaux, Laurence Charles, Béatrice Tuccio. Use of X-band EPR to follow thereaction between various nucleophilic compounds and 2-methyl-2-nitrosopropane (MNP).Anal. Meth. 2011, 3 (7) 1582-1586. DOI: 10.1039/c1ay05149k

5. Mathilde Triquigneaux, Laurence Charles, Christiane André-Barrès, Béatrice Tuccio. Ene-reaction between a dienolic compound and 2-methyl-2-nitrosopropane (MNP): an EPR-MSstudy. Tetrahedron Lett. 2010, 51 (48), 6220-6223. DOI: 10.1016/j.tetlet.2010.09.051

4. Mathilde Triquigneaux, Béatrice Tuccio, Laurence Charles. Combining EPR and ESI-MS/MS to study the reactivity of alkylthiols and cysteine towards 2-methyl-2-nitrosopropane(MNP). Anal. Meth. 2010, 2 (6) 694-700. DOI: 10.1039/c0ay00185f

3. Robert Lauricella, Mathilde Triquigneaux, Christiane Andre-Barres, Laurence Charles,Béatrice Tuccio. 5-Hydroxy-2,2,6,6-tetramethyl-4-(2-methylprop-1-en-1-yl)cyclohex-4-ene-1,3-dione, a novel cheletropic trap for NO EPR detection. Chem. Commun. 2010, 46 (20) 3675-3677. DOI: 10.1039/C002990D

2. Mathilde Triquigneaux, Laurence Charles, Christiane André-Barrès, Béatrice Tuccio. A combined spin trapping / EPR / mass spectrometry approach to study the formation of endoperoxides by dienolic precursor autooxidation. Org. Biomol. Chem. 2010, 8 (6) 1361-1367. DOI: 10.1039/b921694d

1. Mathilde Triquigneaux, Béatrice Tuccio, Robert Lauricella, Laurence Charles. Nucleophileaddition of reduced glutathione on 2-methyl-2-nitroso compound: a combined electronparamagnetic resonance spectroscopy and electrospray tandem mass spectrometry study. J.Am. Soc. Mass Spectrom. 2009, 20 (11) 2013-2020. DOI: 10.1016/j.jasms.2009.07.018

Current position: Analytical project manager, Syneos Health Clinical Solutions – Biot, France

4) PhD Student – 2007-2010 – Supervision rate: 50% (with Dr S Viel)

Rémi GIORDANENGO

Thesis title : Methodological developments in mass spectrometry and nuclear magnetic resonance to investigate the microstructure of copolymers, defended on June 29, 2010

Associated scientific production:

7. Rémi Giordanengo, Stéphane Viel, Manuel Hidalgo, Béatrice Allard-Breton, André Thévand,Laurence Charles. Methylation of acidic moieties in copolymer of poly(methyl methacrylate)and poly(methacrylic acid) for end-group characterization in tandem mass spectrometry. RapidCommun. Mass Spectrom. 2010, 24 (14) 1941-1947. DOI: 10.1002/rcm.4591

6. Rémi Giordanengo, Stéphane Viel, Manuel Hidalgo, Béatrice Allard-Breton, André Thévand, Laurence Charles. Analytical strategy for the molecular weight determination of random copolymers. J. Am. Soc. Mass Spectrom. 2010, 21 (6) 1075-1085. DOI: 10.1016/j.jasms.2010.02.007

5. Rémi Giordanengo, Stéphane Viel, Manuel Hidalgo, Béatrice Allard-Breton, André Thévand, Laurence Charles. Structural characterization of a poly(methacrylic acid)-poly(methylmethacrylate) copolymer by nuclear magnetic resonance and mass spectrometry. Anal. Chim. Acta 2009, 654 (1) 49-58. DOI: 10.1016/j.aca.2009.06.044

4. Stéphane Viel, Michaël Mazarin, Rémi Giordanengo, Trang N. T. Phan, Laurence Charles,Stefano Caldarelli, Denis Bertin. Improved compositional analysis of block copolymers usingdiffusion ordered NMR spectroscopy. Anal. Chim. Acta 2009, 654 (1) 45-48. DOI:10.1016/j.aca.2009.06.049

3. Caroline Barrère, Michaël Mazarin, Rémi Giordanengo, Trang N. T. Phan, André Thévand,Stéphane Viel, Laurence Charles. Molecular weight determination of Block Copolymers byPulsed Gradient Spin-Echo NMR. Anal. Chem. 2009, 81 (19) 8054-8060. DOI:10.1021/ac9018654

2. Rémi Giordanengo, Stéphane Viel, Béatrice Allard-Breton, André Thévand, Laurence Charles. Positive mode electrospray tandem mass spectrometry of poly(methacrylic acid) oligomers. Rapid Commun. Mass Spectrom. 2009, 23 (11) 1557-1562. DOI: 10.1002/rcm.4040

1. Rémi Giordanengo, Stéphane Viel, Béatrice Allard-Breton, André Thévand, Laurence Charles. Tandem mass spectrometry of poly(methacrylic acid) oligomers produced by negative mode electrospray ionization. J. Am. Soc. Mass Spectrom. 2009, 20 (1) 25-33. DOI: 10.1016/j.jasms.2008.09.019

Awards:
“2011 best thesis” award from the French Society for Mass Spectrometry

Current position: Scientific manager, R&D Department, Solvay, King of Prussia (USA)

3) PhD Student – 2006-2009 – Supervision rate: 100%

Marion GIROD

Thesis title : Analytical strategies for mass spectrometry of PEO-b-PS block copolymers, defended on May 6, 2009

Associated scientific production:

7. Marion Girod, Emmanuel Beaudoin, Laurence Charles. Effect of salt in the mobile phase oncritical conditions of poly(ethylene glycol) in liquid chromatography. Anal. Meth. 2009, 1 (2)128-131. DOI: 10.1039/b9ay00118b

6. Marion Girod, Michaël Mazarin, Trang N. T. Phan, Didier Gigmes, Laurence Charles.Determination of block size in poly(ethylene oxide)-b-polystyrene block copolymer by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. J. Polym. Sci. A, Polym.Chem. 2009, 47 (13) 3380-3390. DOI: 10.1002/pola.23414

5. Marion Girod, Trang N. T. Phan, Laurence Charles. Tuning block copolymer structural information by adjusting salt concentration in liquid chromatography at critical conditions coupled with electrospray tandem mass spectrometry. Rapid Commun. Mass Spectrom. 2009, 23 (10) 1476-1482. DOI: 10.1002/rcm.4028

4. Michaël Mazarin, Marion Girod, Stéphane Viel, Trang N. T. Phan, Sylvain R. A. Marque, Stéphane Humbel, Laurence Charles. Role of the adducted cation in the release of nitroxide end-group of controlled polymer in mass spectrometry. Macromolecules 2009, 42 (6) 1849-1859. DOI: 10.1021/ma802372m

3. Marion Girod, Trang N. T. Phan, Laurence Charles. On-line coupling of liquid chromatography at critical conditions with electrospray tandem mass spectrometry for the characterization of a nitroxide-mediated poly(ethylene oxide)/polystyrene block copolymer. Rapid Commun. Mass Spectrom. 2008, 22 (23) 3767-3775. DOI: 10.1002/rcm.3796

2. Marion Girod, Trang N. T. Phan, Laurence Charles. Microstructural study of a nitroxide-mediated poly(ethylene oxide)/polystyrene block copolymer (PEO-b-PS) by electrospraytandem mass spectrometry. J. Am. Soc. Mass Spectrom. 2008, 19 (8) 1163-1175. DOI:10.1016/j.jasms.2008.04.030

1. Marion Girod, Yannick Carissan, Stéphane Humbel, Laurence Charles. Tandem massspectrometry of doubly charged poly(ethylene oxide) oligomers produced by electrosprayionization. Int. J. Mass Spectrom. 2008, 272 (1) 1-11. DOI: 10.1016/j.ijms.2007.12.010

Current position: CNRS researcher, Université Lyon 1 – Lyon, France

2) PhD Student – 2005-2008 – Supervision rate: 100%

Salimo MOHAMED

Thesis title : Ionization techniques in mass spectrometry: origin and extent of mass discrimination for synthetic polymers, defended on November 26, 2008

Associated scientific production:

7. Salimo Mohamed, Laurence Charles. Selectivity of electrospray response in small polymeranalysis by mass spectrometry. Rapid Commun. Mass Spectrom. 2006, 20 (21) 3188-3192.DOI: 10.1002/rcm.2713

1. Laurence Charles, Stéphanie Caloprisco-Buco, Salimo Mohamed, Michelle Sergent.Chemometric approach to evaluate the parameters affecting electrospray: application of astatistical design of experiments for the study of arginine ionization. Eur. J. Mass Spectrom.2005, 11 (4) 361-370. DOI: 10.1255/ejms.759

Current position: High-school teacher – Paris, France

1) PhD Student – 2005-2008 – Supervision rate: 50% (with Dr S. Viel)

Michaël MAZARIN

Thesis title : MALDI as an ionization source for mass spectrometry of synthetic polymers, defended on November 25, 2008

Associated scientific production:

7. Stéphane Viel, Michaël Mazarin, Rémi Giordanengo, Trang N. T. Phan, Laurence Charles, Stefano Caldarelli, Denis Bertin. Improved compositional analysis of block copolymers using diffusion ordered NMR spectroscopy. Anal. Chim. Acta 2009, 654 (1) 45-48. DOI: 10.1016/j.aca.2009.06.049

6. Caroline Barrère, Michaël Mazarin, Rémi Giordanengo, Trang N. T. Phan, André Thévand,Stéphane Viel, Laurence Charles. Molecular weight determination of Block Copolymers byPulsed Gradient Spin-Echo NMR. Anal. Chem. 2009, 81 (19) 8054-8060. DOI:10.1021/ac9018654

5. Hélène Pizzala, Caroline Barrère, Michaël Mazarin, Fabio Ziarelli, Laurence Charles. Solid-state NMR as a tool to explore MALDI sample. J. Am. Soc. Mass Spectrom. 2009, 20 (10)1906-1911. DOI: 10.1016/j.jasms.2009.06.021

4. Marion Girod, Michaël Mazarin, Trang N. T. Phan, Didier Gigmes, Laurence Charles. Determination of block size in poly(ethylene oxide)-b-polystyrene block copolymer by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. J. Polym. Sci. A, Polym. Chem. 2009, 47 (13) 3380-3390. DOI: 10.1002/pola.23414

3. Michaël Mazarin, Marion Girod, Stéphane Viel, Trang N. T. Phan, Sylvain R. A. Marque,Stéphane Humbel, Laurence Charles. Role of the adducted cation in the release of nitroxideend-group of controlled polymer in mass spectrometry. Macromolecules 2009, 42 (6) 1849-1859. DOI: 10.1021/ma802372m

2. Michaël Mazarin, Trang N. T. Phan, Laurence Charles. Using solvent-free preparation topromote protonation of poly(ethylene oxide)s with labile end-groups in matrix-assisted laserdesorption/ionization. Rapid Commun. Mass Spectrom. 2008, 22 (23) 3776-3782. DOI:10.1002/rcm.3798

1. Michaël Mazarin, Stéphane Viel, Béatrice Allard-Breton, André Thévand, Laurence Charles.Use of pulsed gradient spin echo NMR as a tool in MALDI method development for polymermolecular weight determination. Anal. Chem. 2006, 78 (8) 2758-2764. DOI:10.1021/ac0522207

Current position: Scientific manager, R&D Department, TotalEnergies – Solaize, France